This simple syrup is to be used as an equivalent of a regular sugar-based simple syrup in cocktails, coffee and tea drinks, etc. About Agave: Agave is a natural sweetener used in place of sugar. It has a glycemic index that is 40 percent lower than refined sugar and agave nectar is an optional sweetener for people who are diabetic; the sugars from agave nectar are released slowly into the bloodstream, keeping blood sugar at a more consistent level.